Creatinine in urine is a valuable marker for assessing kidney function, muscle health, and hydration levels. It plays a critical role in detecting kidney-related issues and normalizing other biomarker measurements. Abnormal levels, whether high or low, may signal problems that need further investigation or lifestyle adjustments to maintain overall health.
Urinary creatinine levels provide important insights into how well the kidneys are functioning and how the body is handling muscle metabolism. Here's why this biomarker is tested:
- Normal Creatinine Levels
- In healthy individuals, the amount of creatinine in urine is relatively stable and depends on muscle mass, age, sex, and activity level.
- Low Creatinine Levels
- Kidney Dysfunction: When the kidneys are not filtering properly (due to kidney disease or injury), creatinine levels in urine may drop because it stays in the bloodstream.
- Severe Muscle Loss: Conditions like muscle wasting or prolonged immobility can reduce creatinine production, resulting in low levels in urine.
- Overhydration: Excess fluid intake can dilute urine, lowering creatinine concentrations.
- High Creatinine Levels
- Increased Muscle Activity: Intense exercise can temporarily elevate creatinine levels due to increased muscle metabolism.
- Dehydration: Reduced water intake concentrates urine, leading to higher creatinine levels.
- Certain Medications or Supplements: Use of creatine supplements can increase creatinine levels in urine.